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Nanograb

Announcing NGX1, a platform for designing multi-peptide targeted lipid nanoparticles (tLNPs)

launched 19h ago

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Launched on 17 September 2026 from Y Combinator, in the week of 14 September 2026.

What they say it does

TLDR Nanograb is announcing NGX1, a universal navigation system for mRNA drugs to deliver cures for any disease. Moderna proved that mRNA will transform skin cancer care, we expand this to all diseases. Delivery is one of the most important problems stopping life-changing mRNA drugs reaching millions. There are over 3,000 different cell types in the body, but mRNA drug developers can only hit 1% of them. The problem is so pressing that multiple public biopharma partners are paying for early access to NGX1. Works the first time, every time. There are more peptide sequences than atoms in the universe. Most approaches to solve delivery rely on screening thousands of formulations. NGX1’s biophysics-informed models achieved >25% hit rates on the first try across different targets in mice (4x improvement in cancer cells, 15x for immune cells). We hit any cell, any state. All cells have receptors. Their combination makes up a unique fingerprint. Most people try and target individual receptors

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